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Outcome of Hepatitis-E Virus Infection among Pregnant Women Admitted in a Tertiary Care Hospital
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Tayyaba Wasim TW, Javeria Mushtaq JM, Waseem M. Outcome of Hepatitis-E Virus Infection among Pregnant Women Admitted in a Tertiary Care Hospital. JRMC [Internet]. 2022 Oct. 25 [cited 2024 Mar. 29];26(2). Available from: http://journalrmc.com/index.php/JRMC/article/view/1882

Abstract

PURPOSE:  To study the effect of post-operative Non-Steroidal Anti-inflammatory (NSAID) eye drops on macular thickness in patients without diabetic retinopathy measured by Optical Coherence Tomography (OCT)

STUDY DESIGN: Quasi experimental study

PLACE & DURATION OF STUDY:  removed for blind review

METHODOLOGY: Diabetic patients without retinopathy who required cataract surgery for visual rehabilitation were included in study. They were than divided into two groups. Group A included patients who received routine steroid+antibiotic post-operative drops while Group B comprised of patients who received nepafenac (0.1%) eye drops eight hourly in addition to routine post-operative eye drops. All patients underwent standard phacoemulsification and intraocular lens implantation followed by use of NSAID eye drops for a month. OCT measurements were done pre-operatively, 7 and 28 days post operatively.

RESULTS: Comparison of central macular thickness between groups was significant at (Pre & 7 day post op) and insignificant at (7th day & 28th day post op) and (Pre & 28th day post op) i.e. 0.043, 0.834 and 0.084 respectively. However, difference of mean central macular thickness was significant at all follow-up periods i.e.0.003, 0.006, and 0.000

CONCLUSION: Post-operative NSAID in diabetic patients without retinopathy leads to a significant decrease in macular thickness as compared to controls after cataract surgery.

KEY WORDS:

Phacoemulsification, Optical Coherence Tomography, Non-steroidal Anti-Inflammatory Agents

https://doi.org/10.37939/jrmc.v26i2.1882
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