TY - JOUR AU - Soffia Khursheed, Hijab Shah, Mariam Asim, PY - 2018/03/30 Y2 - 2024/03/28 TI - Diagnostic Accuracy of Fine Needle Aspiration Cytology in Soft Tissue Sarcomas JF - Journal of Rawalpindi Medical College JA - JRMC VL - 22 IS - 1 SE - Articles DO - UR - http://journalrmc.com/index.php/JRMC/article/view/851 SP - AB - <p>Background: To study diagnostic validity of fine<br>needle aspiration cytology in soft tissue sarcoma.<br>Methods: In this descriptive study patients of all<br>ages and both gender with obvious soft tissue<br>swellings and patient in whom both FNAC followed<br>by histopathology, were included. Cases with<br>obvious inflammatory lesions were excluded from<br>the study. Immunohistochemistry was employed<br>where required.The diagnosis made on FNAC was<br>then compared with the diagnosis made on<br>histopathology.<br>Results: Mean age of the patients was 28 years±<br>16yrs. Lower extremity tumours were seen in 65%.<br>Most common soft tissue sarcoma on FNAC was<br>spindle cell sarcoma (11 cases) followed by round<br>cell sarcoma(10 cases). Subsequent histopathology of<br>cases showed 55% of benign soft tissue tumours and<br>45% of soft tissue sarcomas. Hence there were 4 false<br>negative cases and one false positive case on<br>cytology. On comparing with histopathological<br>correlation diagnostic accuracy of FNAC in<br>diagnosing soft tissue sarcoma came out to be<br>92.3%.The sensitivity and specificity of FNAC in soft<br>tissue sarcoma was 86.2 % and 97.2% respectively.<br>Conclusion: FNAC is a useful procedure in preoperative<br>diagnosis of benign and malignant soft<br>tissue tumours , with a high sensitivity, specificity<br>and diagnostic accuracy in soft tissue sarcomas.</p> ER -