Diagnostic Accuracy of Red Cell Distribution Width in Mild Iron Deficiency Anaemia in Women of Childbearing Age

  • Jamal Ahmad Department of Pathology ,Foundation Medical College, Rawalpindi
Keywords: Iron deficiency, RDW-CV, Anaemia

Abstract

Background: To determine the accuracy of red cell
distribution width-coefficient of variation (RDWCV)
in detection of mild iron deficiency anaemia in
women of child bearing age by comparing it with
serum ferritin level.
Methods: In this cross-sectional study one hundred
eighty women of child bearing age between 15-45
years with mild anaemia(Haemoglobin 9-11 g/dl)
were selected. Complete blood count (including
RDW-CV) was performed using automated
haematology analyzer Sysmex XT 2000i. RDWCVvalue
of more than 17% was taken as cutoff.
Those patients having RDW-CV>17% and a low
serum ferritin < 15 ng/ml were taken as true
positives while those with RDW-CV <17% and a
high serum ferritin > 15 ng/ ml were taken as true
negatives. False positives were those having a serum
ferritin of > 15 ng/ml and RDW-CV of >17% while
false negative were those having a serum ferritin of
< 15 ng/ml and RDW of < 17%.
Results: Mean age of patients was 30± 4 years.
Seventy (39%) patients were true positive while 65
(36%) patients were true negative. Sixty four patients
(35.5%) were pregnant females and 116(64%) were
non-pregnant females. Among the pregnant patients,
21 patients (32.8%) were true positive. Among nonpregnant
females 69 patients (59.5%) were true
positive.
Conclusion: RDW-CV has diagnostic significance
as an early indicator of iron deficiency.

Published
2016-12-30
How to Cite
1.
Ahmad J. Diagnostic Accuracy of Red Cell Distribution Width in Mild Iron Deficiency Anaemia in Women of Childbearing Age. JRMC [Internet]. 30Dec.2016 [cited 20Jun.2021];20(4):309-11. Available from: https://journalrmc.com/index.php/JRMC/article/view/156
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Articles