Antibiotics prescription pattern in COVID-19 patients presenting in DHQ Teaching Hospital Sahiwal; Is Pakistan heading towards Post-COVID Antibiotic Resistance Era?

  • Muhammad Waseem Sahiwal Medical College, Sahiwal
  • Maryam Rafiq Sahiwal Medical College, Sahiwal
  • Adeela Munir DHQ Teaching Hospital, Sahiwal
  • Zahid Kamal Sahiwal Medical College, Sahiwal
  • Nauman Aziz Sahiwal Medical College, Sahiwal
  • Muhammad Junaid Iqbal Sahiwal Medical College, Sahiwal
Keywords: Antibiotics, antibiotic resistance, COVID-19, drug prescription, SARS-cov-2

Abstract

Background

There is a lack of data about antibiotic prescription trends and patterns of inappropriate antibiotic stewardship in COVID-19 patient management.

 

Objective

To determine frequency and pattern of antibiotic prescription in COVID-19 patients presenting in DHQ teaching hospital, Sahiwal. 

 

Methods

This observational cross-sectional prospective study was conducted from 1st June 2020 to 31st March 2021 in patients admitted in COVID isolation facility of DHQ Teaching hospital, Sahiwal with confirmed COVID-19 infection. Patients of all ages and of both genders were included. Data was collected by a pre-designed proforma. Data included patient’s age, gender, co-morbid conditions, type and duration of antibiotic use, and details of prescribing physicians. Descriptive statistics were applied to determine frequency and percentages of variables.

 

Results

Out of 800 participants, 543(67.8%) were males, and the remaining 257 (32.1%) were females.

The majority 328(41%) of patients belonged to the age group 40-60 years. 639(79.8%) patients had co-morbidities. Diabetes mellitus was the most common co-morbid condition 248 (31%). Antibiotics were prescribed to all patients 800 (100%) before admission to the COVID Isolation facility. The majority of patients 348 (43.5%) had used antibiotics for 3-7 days before admission. Macrolides class was the most commonly prescribed antibiotic 417 (52.1%). General practitioners had more tendency to prescribe antibiotics 509(64%) as compared to medical specialists 212(26.5%) and pulmonologists79 (9.8%).

 

Conclusion

Antibiotic stewardship needs to be improved in COVID-19 patients and prescription should be evidence-based aided by laboratory tests. The development of local guidelines for judicious antibiotic prescription in COVID-19 will help in preventing antibiotic resistance.

 

Key Words

Antibiotics, antibiotic resistance, COVID-19, drug prescription, SARS-cov-2

Author Biographies

Muhammad Waseem, Sahiwal Medical College, Sahiwal

MBBS, FCPS Pulmonology

Assistant Professor& HOD Pulmonology

Sahiwal Medical College, Sahiwal

Adeela Munir, DHQ Teaching Hospital, Sahiwal

MBBS

Woman Medical Officer

DHQ Teaching Hospital, Sahiwal

Zahid Kamal, Sahiwal Medical College, Sahiwal

MBBS, FCPS, FRCS

Professor and Principal Ophthalmology

Sahiwal Medical College Sahiwal

Nauman Aziz, Sahiwal Medical College, Sahiwal

MBBS, M.Phil. Physiology

Assistant Professor Physiology

Sahiwal Medical College, Sahiwal

Muhammad Junaid Iqbal, Sahiwal Medical College, Sahiwal

 MBBS

Assistant Director Medical Education

Sahiwal Medical College, Sahiwal.

 

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Published
2021-08-31
How to Cite
1.
Waseem M, Rafiq M, Munir A, Kamal Z, Aziz N, Iqbal M. Antibiotics prescription pattern in COVID-19 patients presenting in DHQ Teaching Hospital Sahiwal; Is Pakistan heading towards Post-COVID Antibiotic Resistance Era?. JRMC [Internet]. 31Aug.2021 [cited 25Oct.2021];25(1):105-9. Available from: http://journalrmc.com/index.php/JRMC/article/view/1656