Official publication of Rawalpindi Medical University
Frequency of Corrected QT Interval in Patients With Cirrhosis
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1.
Mashhood Ali, Arslan Shahzad, Inayatullah Khan Adil, Shan Alam, Haseeb Noor,Asif Imran ,Naveed Ganito. Frequency of Corrected QT Interval in Patients With Cirrhosis. JRMC [Internet]. 2016 Jun. 30 [cited 2024 Mar. 29];20(2). Available from: http://journalrmc.com/index.php/JRMC/article/view/185

Abstract

Background:. To assess the frequency of QTc
prolongation in patients with liver cirrhosis and to
observe its association with the severity of cirrhosis.
Methods: This cross-sectional observational study
included 189 diagnosed cases of liver cirrhosis who
were consecutively recruited and categorized
according to Child-Pugh class, to rate the severity.
QTc interval prolongation was observed, and its
association with Child-Pugh class scores (severity of
Liver Cirrhosis) was assessed using Chi-square test
keeping p-value less than 0.05 as statistically
significant.
Results: The mean age of the participants was 51.25
±14.34, and gender distribution showed that96 (51%)
were male and 93 (49%) were female. Q-Tc interval
was normal in 99 (52%) patients and was prolonged
in 90 (48%) patients. The QT-c interval prolongation
was significantly associated with severity of liver
cirrhosis. (p-value =0.000)
Conclusion: QTc interval was prolonged in almost
half of the patients and the frequency of prolonged
QTc was directly proportional to the severity of the
hepatic cirrhosis according to Child-Pugh criteria

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