Official publication of Rawalpindi Medical University
Assessment of Factor VII Levels in Patients of Chronic Liver Disease
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How to Cite

1.
Nabeela Naeem , Muhammad Ayyub , Fazal-ur –Rehman. Assessment of Factor VII Levels in Patients of Chronic Liver Disease. JRMC [Internet]. 2013 Jun. 30 [cited 2024 Mar. 28];17(1). Available from: http://journalrmc.com/index.php/JRMC/article/view/499

Abstract

Background : To determine the levels of coagulation factor VII in patients of chronic liver disease.
Methods: In this descriptive study sixty known patients of chronic liver disease were included. Patients were stratified into three groups on the basis of Child-Pugh scoring system, utilizing ascites, bilirubin, albumin, prothrombin time and encephalopathy as markers of disease activity. The correlation of Child-Pugh scoring system with factor VII levels was analyzed
Results: Majority ( 63.33%) were males . Mean age was 50.5 years. Majority of patients (82%) had deficient Factor VII levels. Factor VII levels revealed a declining trend from Child-Pugh class B to C.
Conclusion: Due to its short half-life factor VII level can serve as a helpful marker in diagnosing the degree of liver damage and as a prognostic indicator during the course of treatment.

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