Number of Hofbauer Cells in Placentae from Normal and Pre Eclamptic Gestation

  • Ifra Saeed Department of Anatomy Rawalpindi Medical University
  • Ayesha Yousaf Department of Anatomy Rawalpindi Medical University
  • Shaista Ali Department of Anatomy , HBS Medical and Dental College
Keywords: Placenta, Pre-eclampsia, Hofbauer cells

Abstract

Background:. To compare the number of
Hofbauer cell in placenta from normal pregnancy
with placenta complicated by pre eclampsia
Methods: For this comparative study, fifty
placentae were taken from normotensive mothers
(Normotensive group) and fifty placentae were taken
from mothers with hypertension (Hypertensive
group). Placentae were fixed in formalin for 48
hours. Placentae were divided into four parts, after
fixation and 5mm tissue was taken from the center of
randomly selected two parts. After tissue processing
and staining, number of Hofbauer cells was
counted in both groups.
Results: The number of Hofbauer cells was
increased in hypertensive group. The quantitative
difference between number of Hofbauer cells in
normotensive and hypertensive groups were
statistically significant.
Conclusion: Number of Hofbauer cells was
increased in hypertensive group and it may be the
result of placental hypoxia which is a common
finding in pre eclampsia

Published
2018-03-30
How to Cite
Saeed, I., Yousaf, A., & Ali, S. (2018). Number of Hofbauer Cells in Placentae from Normal and Pre Eclamptic Gestation. Journal of Rawalpindi Medical College, 76-78. Retrieved from http://journalrmc.com/index.php/JRMC/article/view/853