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Zinc Deficiency in Patients of Chronic Hepatic Encephalopathy

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Shabana Lakho, Prem Kumar, . Ehsan Rahim Memon. Zinc Deficiency in Patients of Chronic Hepatic Encephalopathy. JRMC [Internet]. 2018 Sep. 30 [cited 2024 Apr. 12];. Available from:


Background : To determine the zinc deficiency in patients with chronic hepatic encephalopathy
Methods: In this cross section study decompensated hepatic cirrhosis diagnosed patients (n=102) aged>16 years,both gender, with hepatic encephalopathy as per its grades were included. Blood samples were drawn and serum zinc levels were estimated.
Results: Mean-age of patients was 51.5±9.5 years. Men (64.7%) constituted the main. Zinc deficiency was noted in 68.6% patients. Hepatic encephalopathy grade II was most common (42.2%) . Hepatic encephalopathy grading, II, III and IV were found significantly associated with zinc deficiency (p-value= 0.007). No significant difference was found in zinc deficiency according to age p-value 0.739. Zinc deficiency was significantly higher among males (p-value 0.043).
Conclusion: Zinc deficiency was quite high (68.6%),with hepatic encephalopathy. Zinc deficiency was more common in males and middle age group patients.

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