Comparison of Vitamin D Levels in Patients with Dengue Haemorrhagic Fever and Dengue Fever

  • Muhammad Rizwan Mahmud Department of Medicine, Medical Unit I, Benazir Bhutto Hospital and Rawalpindi Medical University;
  • Sadaf Zaman Department of Medicine, Medical Unit I, Benazir Bhutto Hospital and Rawalpindi Medical University;
  • Nadeem Naseem Department of Biochemistry , Rawalpindi Medical University
  • Nadeem Iqbal Department of Medicine, Medical Unit I, Benazir Bhutto Hospital and Rawalpindi Medical University
  • Nida Tanveer Department of Medicine, Medical Unit I, Benazir Bhutto Hospital and Rawalpindi Medical University;
  • Mohammad Ali Khalid Department of Medicine, Medical Unit I, Benazir Bhutto Hospital and Rawalpindi Medical University
  • Haider Zaigham Baqai Department of Medicine, Medical Unit I, Benazir Bhutto Hospital and Rawalpindi Medical University

Abstract

Background: To compare vitamin D levels in patients of dengue hemorrhagic fever with dengue fever
Methods: A total of 50 patients with diagnosed dengue fever, who fulfilled the inclusion criteria were enrolled in the study. Patients were divided into two groups having 25 participants each; one group had Dengue fever (DF) while the other was suffering from dengue hemorrhagic fever (DHF). Vitamin D was estimated by the chemiluminescence method. Pearson’s Chi-square was applied to compare the proportion of patients in each study group. Relative Risk was measured along with 95% confidence interval. Significant p-value was < 0.05.
Results: Mean age of patients was 37.79 ± 15.2 years (range: 16-90 years). There were 74% males and 26% females. Mean vitamin D levels in dengue fever patients were higher (21.5 ± 13.6 ng/ml) as compared to Dengue hemorrhagic fever (12.4 ± 5.6 ng/ml). The difference was statistically significant (p=0.003).
Conclusions: Vitamin D may have a role in the management of dengue fever. Low levels of vitamin D might be associated with dengue hemorrhagic fever.

Published
2018-06-30
How to Cite
Mahmud, M. R., Zaman, S., Naseem, N., Iqbal, N., Tanveer, N., Khalid, M. A., & Baqai, H. Z. (2018). Comparison of Vitamin D Levels in Patients with Dengue Haemorrhagic Fever and Dengue Fever. Journal of Rawalpindi Medical College, 22, 92-95. Retrieved from http://journalrmc.com/index.php/JRMC/article/view/870
Section
Articles