Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy

  • Uzma Saeed Department of Radiology,Dallah Hospital,Riyadh, Saudi Arabia
Keywords: Pregnancy, Ectopic, Chorionic Gonadotropin, Transvaginal ultrasonography


To correlate Beta Hcg Levels with
transvaginal sonographic features of ectopic
Methods: In this prospective study 204 patients
with confirmed diagnosis of ectopic pregnancy (EP),
by both trasnvaginal sonography (TVS) and
histopathology were included . Results of TVS and
serum βHCG levels were obtained. Other variables
were age, gestational age, size, site and volume of
EP, fetal cardiac activity and presence or absence of
pelvic ascites.
Results: Sensitivity and specificity of TVS for
detection of EP was 98% and 87.5% respectively. The
values of median and range for the age, gestational
age, βHCG and volume of EP were 29 (17-43) years,
5(4-6) weeks, 3248.5 (14-53048) IU/L, 8648.36 (268-
80491) mm3 respectively. Most common site of EP
was adnexa (93.6%) and most common side was right
(52%). Fetal cardiac activity was evident in 4.4%
cases and pelvic ascites was present in 64.7% cases.
There was no significant difference between two
βHCG groups (<2000, >2000) in terms of qualitative
and quantitative variables except the volume of EP
which was significantly different among groups (p
value <0.0001).
Conclusion: Serum βHCG level alone cannot
diagnose or exclude EP confidently and it is
significantly correlated with the size of EP. The
combination of serum βHCG and TVS provide
highly accurate diagnostic information.

How to Cite
Saeed U. Correlating Serum Beta hCG Levels with Transvaginal Sonographic Features of Ectopic Pregnancy. JRMC [Internet]. 30Mar.2017 [cited 9May2021];21(1):64-7. Available from: