Relationship of Esophageal Strictures with Esophageal Injury after Corrosive Intake
Background: To study the relationship of esophageal strictures with esophageal injury after corrosive intake
Methods: In this cross-sectional study 142 patients with a history of corrosive intake and positive clinical findings were recruited. Patients underwent upper gastrointestinal endoscopy during the first 48 hours after ingestion in order to assess the extent of injury according to the grading system and after 6 weeks, endoscopy was repeated for documentation of stricture formation.
Results: Sixty two(43.7%) patients had severe esophageal injury 80 (56.3%) had mild injury. At 6 weeks, repeat endoscopy showed stricture formation among 34 (23.9% patients while 108 (76.05%) did not develop any stricture. Only 8.7% patients with mild esophageal injury developed stricture compared to 27 (43.5%) patients with severe esophageal injury (relative Risk 4.97, 95% Confidence Interval 2.32 to 10.66, p-value 0.00) and this difference was highly statistically significant.
Conclusion: Patients with high-grade esophageal injury have progressively higher frequency of stricture formation after corrosive intake.
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