Changes in Arrangement of Chondrons in Radial Zone of Ageing Male Human Articular Cartilage

Abstract

Background: To study the variation in
arrangement of chondrons in radial zone of male
human articular cartilage.
Methods: Forty samples of articular cartilage from
male dead bodies ageing between 21 – 60 years were
collected and divided into four groups. After tissue
processing and cutting, H&E and special staining
with Masson’s Trichrome was done and arrangement
of chondrons was noted.
Results: With advancing age the arrangements of
chondrons in radial zone of group A, B and C was in
short columns while in group D, the arrangement
was disturbed. The chondrons were observed in
pairs and clusters.
Conclusion: In ageing articular cartilage the
arrangements of chondrons in radial zone of
articular cartilage is altered leading to osteoarthritis
that makes it focus of intense study for preventive
measures and treatment.