Official publication of Rawalpindi Medical University
Incidence Of Helicobacter Pylori Infection in Association With ABO Blood Groups

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ABO Blood Group, Peptic Ulcer, Seronegative, Seropositive

How to Cite

Zehra A, Sabir M, Sarwar S, Ishfaq A, Ahmad K, Saleem A. Incidence Of Helicobacter Pylori Infection in Association With ABO Blood Groups . JRMC [Internet]. 2024 Mar. 29 [cited 2024 Jul. 17];28(1). Available from:


Objective: The study aimed to investigate the association between ABO blood groups and helicobacter infection.

Method: 150 participants, including 93 females and 57 males between the age group of 18-60 years, were involved in the study. A sample of 3 ml blood was collected and screened against H. pylori antibodies (IgG) by H. pylori rapid diagnostic kit. ABO and Lewis antigen phenotypes were determined with a macroscopic agglutination technique.

Results: According to the study's findings, there were 55.42% women (46/83) and 44.5% men (37/83) among the 83 seropositive patients, while 70.14% women (47/67) and 29.85% men (20/67) were found among the 67 seronegative patients. The findings of this study reveal that those with the blood groups O+ and B+ have an estimated 25.3% (21/83) higher risk of H. pylori infection, whereas when seronegative individuals were investigated, it was discovered that blood groups 0+ were also leading, 28.4% (19/67), indicating that there was no significant difference between H. pylori seropositive and seronegative patients (p-value = 0.5146). Other factors, such as gender and family history, did not significantly affect the incidence of H. pylori.  

Conclusion:  It was concluded from the study that no significant difference was observed between trends of H. pylori seropositive patients and seronegative individuals having different blood groups.

Keywords: ABO Blood Group, Peptic Ulcer, Seronegative Pyloric patients, Seropositive Pyloric patients.
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Copyright (c) 2024 Amina Zehra, Maimoona Sabir, Sumaira Sarwar, Afsheen Ishfaq, Kishmain Ahmad, Afshan Saleem