Official publication of Rawalpindi Medical University
Risk Factors of Infection in Total Knee Arthroplasty

How to Cite

Junaid Khan, Riaz Ahmed, Tehreem Zahid, Rahman Rasool Akhtar. Risk Factors of Infection in Total Knee Arthroplasty. JRMC [Internet]. 2017 Sep. 30 [cited 2024 May 29];21(3). Available from:


Background: To determine risk factors of infection in total knee arthroplasty
Methods: In this descriptive study all patients undergoing primary total knee arthroplasty were included. Patients were followed post-operatively at 2,4,8,12 and 24 weeks. Signs of inflammation and inflammatory markers such as total leukocyte count (TLC), C-reactive protein (CRP) and ESR were measured. Risk factors like age, body mass index (BMI), ASA, co-morbid conditions were also noted.
Results: Out of the 78 patients osteoarthritis (94.87%) was the pre-dominant cause of total knee replacement (TKR). 6.41% cases got infected. In majority of the infected cases (60%), Staphylococcus aureus was the infective organism. Diabetes Mellitus (p=0.01) and Obesity (p=0.02) had a significant relation to post-operative infection.
Conclusion: Pre-operative risk evaluation and prevention strategies along with early recognition of infection and control can greatly reduce the risk of joint infection post-TKR which will not only improve the mobility of patient but also its morbidity and mortality as well