Official publication of Rawalpindi Medical University
Number of Hofbauer Cells in Placentae from Normal and Pre Eclamptic Gestation
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How to Cite

1.
Ifra Saeed , Ayesha Yousaf , Shaista Ali. Number of Hofbauer Cells in Placentae from Normal and Pre Eclamptic Gestation. JRMC [Internet]. 2018 Mar. 30 [cited 2024 Mar. 28];22(1). Available from: https://journalrmc.com/index.php/JRMC/article/view/853

Abstract

Background:. To compare the number of
Hofbauer cell in placenta from normal pregnancy
with placenta complicated by pre eclampsia
Methods: For this comparative study, fifty
placentae were taken from normotensive mothers
(Normotensive group) and fifty placentae were taken
from mothers with hypertension (Hypertensive
group). Placentae were fixed in formalin for 48
hours. Placentae were divided into four parts, after
fixation and 5mm tissue was taken from the center of
randomly selected two parts. After tissue processing
and staining, number of Hofbauer cells was
counted in both groups.
Results: The number of Hofbauer cells was
increased in hypertensive group. The quantitative
difference between number of Hofbauer cells in
normotensive and hypertensive groups were
statistically significant.
Conclusion: Number of Hofbauer cells was
increased in hypertensive group and it may be the
result of placental hypoxia which is a common
finding in pre eclampsia

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