Official publication of Rawalpindi Medical University
Abnormally Invasive Placenta Diagnosed On Ultrasonography Among High-Risk Women With Placenta Previa

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1.
Waheed F, Batool F, Raza A. Abnormally Invasive Placenta Diagnosed On Ultrasonography Among High-Risk Women With Placenta Previa . JRMC [Internet]. 2025 Jun. 30 [cited 2025 Jul. 17];29(2). Available from: https://journalrmc.com/index.php/JRMC/article/view/2879

Abstract

Objective:

The main aim of the study was to find the frequency of abnormally invasive placentas diagnosed on ultrasonography among high-risk women with placenta previa and to assess the association of all three types of placental invasion with placenta previa in prior pregnancies, advanced maternal age and multiple gestations

Methods: This descriptive, cross-sectional study was conducted at CMH Medical College, Lahore, from September 2024 to January 2025 after the approval of the ethical review committee. The data analysis procedure was systematically executed using IBM SPSS 26.0. The Chi-square test was applied.

Results: The study included 165 participants, aged 26-40 years, with 74.5% (n=123) experiencing vaginal bleeding and 95.8% reporting pelvic pain. Among the cases analysed, 93.9% (n=155) were diagnosed with placenta accreta, while placenta increta was observed in 4.2% (n=7), and placenta percreta in 1.8% (n=3). All participants had a history of previous uterine surgery (100%), and 50.3% (n=83) had a prior history of placenta previa. Regarding placenta previa grades, Grade 1 was the most common (67.9%, n=112), followed by Grade 2 (25.5%, n=42), Grade 3 (4.8%, n=8), and Grade 4 (1.8%, n=3). A positive history of placenta previa was found in 32.7% of Grade 1 cases, 13.3% of Grade 2, and 3.0% of Grade 3. Notably, a positive history of placenta previa was linked to higher rates of placenta accreta, especially in women aged ≥35 years (4.2%).

Conclusion: Among high-risk women with placenta previa, abnormally invasive placenta (AIP) is a serious obstetric complication that poses significant feto-maternal risks. For the early and accurate diagnosis of AIP, Ultrasound is the modality of choice, as it is real-time, inexpensive and radiation-free, making timely interventions and improved perinatal outcomes.

Keywords: Placenta Previa, Placenta Accreta, Placenta Percreta, Placenta Increta, Pregnancy, High-Risk.

 

 

https://doi.org/10.37939/jrmc.v29i2.2879

References

Juliana M, Nurlianto Y. Prevalence, Management of Placenta Previa, and Pregnancy Outcomes: An Update Systematic Review. The International Journal of Medical Science and Health Research. 2024;1(2):164-78. https://creativecommons.org/licenses/by-nc/4.0/

Kayem G, Seco A, Vendittelli F, Crenn Hebert C, Dupont C, Branger B, et al. Risk factors for placenta accreta spectrum disorders in women with any prior cesarean and a placenta previa or low lying: a prospective population-based study. Scientific Reports. 2024;14(1):6564. https://doi.org/10.1038/s41598-024-56964-9

Bachmann C, Abele H, Hoopmann M. Placenta Previa et Percreta: A Potentially Life-Threatening Condition. Diagnostics. 2023;13(3):539.

https://doi.org/10.3390/diagnostics13030539

Iacovelli A, Liberati M, Khalil A, Timor-Trisch I, Leombroni M, Buca D, Milani M, Flacco ME, Manzoli L, Fanfani F, Calì G. Risk factors for abnormally invasive placenta: a systematic review and meta-analysis. The Journal of Maternal-Fetal & Neonatal Medicine. 2020 Feb 1;33(3):471-81.

https://doi.org/10.1080/14767058.2018.1493453

Illsley NP, DaSilva-Arnold SC, Zamudio S, Alvarez M, Al-Khan A. Trophoblast invasion: Lessons from abnormally invasive placenta (placenta accreta). Placenta. 2020 Dec 1;102:61-6.

https://doi.org/10.1016/j.placenta.2020.01.004

Al-Khan A, Youssef YH, Feldman KM, Illsley NP, Remache Y, Alvarez-Perez J, Mannion C, Alvarez M, Zamudio S. Biomarkers of abnormally invasive placenta. Placenta. 2020 Feb 1;91:37-42.

https://doi.org/10.1016/j.placenta.2020.01.007

Eliwa S, Abdel Fatah M, El Noury M, El Sayed M. Uterine Artery Doppler and Placental Morphological Features as Predictors of Peripartum Complications in Placenta Previa and Placenta Previa Accreta. Benha medical journal. 2021;38(1):14-26.

https://doi.org/10.21608/bmfj.2021.138621

Anderson-Bagga FM, Sze A. Placenta Previa. 2023 Jun 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 30969640.

https://www.ncbi.nlm.nih.gov/books/NBK539818/

Cochran WG. Sampling techniques: john wiley & sons; 1977.

https://www.scirp.org/journal/home?issueid=5979

Happe SK, Rac MW, Moschos E, Wells CE, Dashe JS, McIntire DD, et al. Prospective first‐trimester ultrasound imaging of low implantation and placenta accreta spectrum. Journal of Ultrasound in Medicine. 2020;39(10):1907-15.

https://doi.org/10.1002/jum.15295

Khan B, Jabeen SS, Khan FS, Mumtaz F, Gul R, Nawaz Q. Maternal And Fetal Outcome in Placenta Previa: A Multicenter Prospective Observational Study. Journal of Rawalpindi Medical College. 2024 Mar 28;28(1).

http://dx.doi.org/10.21276/ijcmr.2020.7.3.8

Iacovelli A, Liberati M, Khalil A, Timor-Trisch I, Leombroni M, Buca D, et al. Risk factors for abnormally invasive placenta: a systematic review and meta-analysis. The Journal of Maternal-Fetal & Neonatal Medicine. 2020;33(3):471-81.

https://doi.org/10.1080/14767058.2018.1493453

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Copyright (c) 2025 Fatima Waheed, Fatima Batool, Asim Raza