Effect of Age and Sex on Left Atrial and Left Ventricular Diastolic Diameters in Patients with Mild Diastolic Dysfunction (Grade I)

  • Muhammad Saeed Department of Cardiology, Holy Family Hospital and Rawalpindi Medical College, Rawalpindi
Keywords: Diastolic diameters,Mild Diastolic, Dysfunction (Grade I), Atrium, Ventricle

Abstract

Background: To analyze the relationship between age, sex, left atrial and left ventricular diastolic diameters in patients with mild diastolic dysfunction.
Methods: In this cross-sectional observational study patients (n=434) diagnosed with mild or grade 1 diastolic dysfunction on Pulse Wave Doppler Echocardiography (E/A<0.8, E/e’<8, abnormal DT) were included. Patients with valvular abnormalities and pericarditis were excluded. Diastolic left atrial and ventricular sizes were determined on echocardiography as per guidelines.
Results:Sex did not show any significant correlation with left atrial and left ventricular diameters (p>0.05). Age was having moderate correlation with left atrial diameter (r=0.49). Age was having negative correlation with left ventricular diameter (r=-0.29) and this was statistically significant (p<0.01). On linear regression analysis, age was the only statistically significant variable that had an un-standardized beta coefficient (B) of 0.207 for left atrial diameter, and -0.7 for left ventricular diameter.
Conclusion:Age was significantly correlated with left atrial and left ventricular diastolic diameters in patients with grade 1 diastolic dysfunction while sex was not statistically significant. On linear regression, age was the only significant factor in predicting left atrial and left ventricular diastolic diameter

Published
2018-01-27
How to Cite
1.
Saeed M. Effect of Age and Sex on Left Atrial and Left Ventricular Diastolic Diameters in Patients with Mild Diastolic Dysfunction (Grade I). JRMC [Internet]. 27Jan.2018 [cited 20Jun.2021];20(4):258-61. Available from: https://journalrmc.com/index.php/JRMC/article/view/131
Section
Articles