Official publication of Rawalpindi Medical University
Association of Central Corneal Thickness among Myopic and Emmetropic Patients Visiting Ophthalmology Department of a Tertiary Care Hospital in Islamabad.

Supplementary Files

PDF

Keywords

Myopes, Emmetropes, CCT 

How to Cite

1.
Khan SA, Shah M, Sharif A, Ullah S, Imdad A, Khalid A. Association of Central Corneal Thickness among Myopic and Emmetropic Patients Visiting Ophthalmology Department of a Tertiary Care Hospital in Islamabad. JRMC [Internet]. 2023 Apr. 1 [cited 2024 Apr. 24];27(1). Available from: https://journalrmc.com/index.php/JRMC/article/view/2033

Abstract

Aim The aim of the study was to determine difference between central corneal thickness (CCT) among myopic and emmetropic eyes. 

Material and Methods A total of 186 participants participated in this comparative cross-sectional study. Sample size was calculated using the WHO calculator and enrolled by consecutive sampling technique. Detail eye examinations were performed of anterior and posterior segments with slit-lamp and refractive status were determined with Auto-refractometer (Nidek ARK 1a) and Pachymetry with Specular Microscope (Topcon SP2000P). The analysis of data was performed in SPSS 22. 

Results To carry out the study, 186 candidates volunteered their time and effort. Male and female participants were included in the study. About 56% of the candidates were men, and 44% were women. Individuals' ages varied from 16 to 49, on average (16-49). As for the control group, the average central corneal thickness was 522.30 microns and standard deviation of ± 29.563. Their sizes varied from 439 microns to 619 microns. The average CCT of myopic people was 515.18 microns, and the standard deviation was ±28.972 microns. The relationship between CCT in myopic eyes and CCT in emmetropic eyes was analysed using a paired t test. The P value was only 0.09, the relevance of the test was not significant. 

Conclusion: CCT difference between myopic and emmetropic eyes was no statistically significant (P 0.09).  

 

https://doi.org/10.37939/jrmc.v27i1.2033

References

Chia EM, Mitchell P, Ojaimi E, Rochtchina E, Wang JJ. Assessment of vision-related quality of life in an older population subsample: The Blue Mountains Eye Study. Ophthalmic epidemiology. 2006 Jan 1;13(6):371-7. https://doi.org/10.1080/09286580600864794

Shah M, Ullah S, Khan SA, Naroo SA. Myopia Progression During COVID19 Pandemic at a Tertiary Care Hospital. Malaysian Journal of Medical Research (MJMR). 2022 Jul 1;6(3):19-29, https://doi.org/10.31674/mjmr.2022.v6i03.003

Chinawa NE, Pedro-Egbe CN, Ejimadu CS. Association between myopia and central corneal thickness among patients in a Tertiary Hospital in South-South Nigeria. Adv. Ophthalmol. Vis. Syst. 2016;5(2):147. DOI: 10.15406/aovs.2016.05.00147

Fricke TR, Jong M, Naidoo KS, Sankaridurg P, Naduvilath TJ, Ho SM, Wong TY, Resnikoff S. Global prevalence of visual impairment associated with myopic macular degeneration and temporal trends from 2000 through 2050: systematic review, meta-analysis and modelling. British Journal of Ophthalmology. 2018 Jul 1;102(7):855-62. doi:10.1016/j.ophtha.2016.01.006

Kotb M, Eissa SA. Correlation between myopic refractive error, corneal power and central corneal thickness in the Egyptian population. Clinical Ophthalmology (Auckland, NZ). 2021;15:1557. https://doi.org/10.2147%2FOPTH.S304693

Santhiago MR, Giacomin NT, Smadja D, Bechara SJ. Ectasia risk factors in refractive surgery. Clinical Ophthalmology (Auckland, NZ). 2016;10:713. https://doi.org/10.2147%2FOPTH.S51313

Divya K, Ganesh MR, Sundar D. Relationship between myopia and central corneal thickness–A hospital based study from South India. Kerala Journal of Ophthalmology. 2020 Jan 1;32(1):45. DOI: 10.4103/kjo.kjo_95_19

Kunert KS, Bhartiya P, Tandon R, Dada T, Christian H, Vajpayee RB. Central corneal thickness in Indian patients undergoing LASIK for myopia. Journal of Refractive Surgery. 2003 May 1;19(3):378-9. https://doi.org/10.3928/1081-597X-20030501-18

European Glaucoma Prevention Study Group. Central corneal thickness in the European glaucoma prevention study. Ophthalmology. 2007 Mar 1;114(3):454-9. https://doi.org/10.1016/j.ophtha.2006.07.039

Steinmetz JD, Bourne RR, Briant PS, Flaxman SR, Taylor HR, Jonas JB, Abdoli AA, Abrha WA, Abualhasan A, Abu-Gharbieh EG, Adal TG. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study. The Lancet Global Health. 2021 Feb 1;9(2):e144-60. doi.org/10.1016/S2214-109X(20)30489-7

Bourne R, Steinmetz JD, Flaxman S, Briant PS, Taylor HR, Resnikoff S, Casson RJ, Abdoli A, Abu-Gharbieh E, Afshin A, Ahmadieh H. Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study. The Lancet global health. 2021 Feb 1;9(2):e130-43. https://doi.org/10.1016/S2214-109X(20)30425-3

Garcia-Medina M, Garcia-Medina JJ, Garrido-Fernandez P, Galvan-Espinosa J, Martin-Molina J, Garcia-Maturana C, Perez-Pardo S, Pinazo-Duran MD. Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships. Clinical Ophthalmology (Auckland, NZ). 2011;5:249. doi: 10.2147/OPTH.S16594

Srivannaboon S. Relationship between corneal thickness and level of myopia. Journal of the Medical Association of Thailand= Chotmaihet thangphaet. 2002 Feb 1;85(2):162-6.

Bamashmus MA, Saleh MF, Mousa A, Abdulrahman M, Fawzi M. Central corneal pachymetry in Yemeni patients undergoing refractive surgery. Saudi Med J. 2014 Jan 1;35(1):56-62.

Srivannaboon S. Relationship between corneal thickness and level of myopia. Journal of the Medical Association of Thailand= Chotmaihet thangphaet. 2002 Feb 1;85(2):162-6.

Mimouni M, Flores V, Shapira Y, Graffi S, Levartovsky S, Sela T, Munzer G, Kaiserman I. Correlation between central corneal thickness and myopia. International Ophthalmology. 2018 Dec;38(6):2547-51. doi: 10.1007/s10792-017-0766-1.

Bueno-Gimeno I, España-Gregori E, Gene-Sampedro A, Lanzagorta-Aresti A, Piñero-Llorens DP. Relationship among corneal biomechanics, refractive error, and axial length. Optometry and Vision Science. 2014 May 1;91(5):507-13. DOI: 10.1097/OPX.0000000000000231

Wei W, Fan Z, Wang L, Li Z, Jiao W, Li Y. Correlation analysis between central corneal thickness and intraocular pressure in juveniles in Northern China: the Jinan city eye study. PLoS One. 2014 Aug 22;9(8):e104842.

Nair Shobita., et al. “Correlation of Central Corneal Thickness with Refractive Errors and Corneal Curvature in the South Indian Population". Acta Scientific Ophthalmology 4.4 (2021): 31-38.

Lee S, Kim B, Oh TH, Kim HS. Correlations between magnitude of refractive error and other optical components in Korean myopes. Korean Journal of Ophthalmology. 2012 Oct 1;26(5):324 DOI: https://doi.org/10.3341/kjo.2012.26.5.324

Koucheki B, Mehravaran S, Hashemi H. Correlation between central corneal thickness and refractive indices in a laser refractive surgery population.

Liu Z, Pflugfelder SC. The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity. Ophthalmology. 2000 Jan 1;107(1):105-11. doi: 10.1016/s0161-6420(99)00027-5

Cho P, Lam C. Factors affecting the central corneal thickness of Hong Kong-Chinese. Current eye research. 1999 Jan 1;18(5):368-74. doi: 10.1076/ceyr.18.5.368.5347.

Pedersen L, Hjortdal J, Ehlers N. Central corneal thickness in high myopia. Acta Ophthalmologica Scandinavica. 2005 Oct;83(5):539-42. doi: 10.1111/j.1600-0420.2005.00498.x.

Krishnan VM, Jayalatha K, Vijayakumar C. Correlation of central corneal thickness and keratometry with refraction and axial length: a prospective analytic study. Cureus. 2019 Jan 19;11(1).. doi: 10.7759/cureus.3917.

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Copyright (c) 2023 Sufian Ali Khan, Mutahir Shah, Ahad Sharif, Saif Ullah, Anjum Imdad, Ayesha Khalid