Abstract
Objective: This descriptive case series aimed to determine the frequency of feto-maternal outcomes in pregnant women with iron deficiency anaemia at the Mardan Medical Complex, Mardan. The study was conducted between December 2020 and May 2021 in the Department of Obstetrics and Gynecology.
Methods: A total of 125 pregnant women diagnosed with anaemia were included in the study. Participants were followed up until delivery, and fetomaternal outcomes, including gestational hypertension, preeclampsia, postpartum haemorrhage, prolonged labour, low Apgar score, low birth weight, preterm delivery, and early neonatal death, were recorded based on predefined operational definitions.
Results: The study participants ranged from 18 to 40 years, with a mean age of 27.784±3.13 years. The mean gestational age was 30.112±2.89 weeks. Among the participants, gestational hypertension was observed in 47.2% of patients, preeclampsia in 60.8%, postpartum haemorrhage in 33.6%, prolonged labour in 40%, low Apgar score in 50.4%, low birth weight in 30.4%, preterm delivery in 28.8%, and early neonatal death in 8%.
Conclusions: The study findings suggest that maternal anaemia, specifically iron deficiency anaemia, increases the risk of adverse maternal and neonatal outcomes. It is crucial to closely monitor and promptly treat pregnant women with iron anaemia to reduce the risk of feto-maternal complications.
Keywords: Pregnancy, Iron deficiency anemia, Feto-maternal outcomes.
References
Hershko C, Hoffbrand AV, Keret D, Souroujon M, Maschler I, Monselise Y, Lahad A. Role of autoimmune gastritis, Helicobacter pylori and celiac disease in refractory or unexplained iron deficiency anaemia. Haematologica. 2005 Jan 1;90(5):585-95.
Milman N. Anemia—is still a major health problem in many parts of the world! Annals of haematology. 2011 Apr;90:369-77.
Joshi M, Gumashta R. Weekly iron folate supplementation in adolescent girls–an effective nutritional measure for the management of iron deficiency anemia. Global Journal of Health Science. 2013 May;5(3):188.
Algarin C, Karunakaran KD, Reyes S, Morales C, Lozoff B, Peirano P, Biswal B. Differences in brain connectivity in adulthood are present in subjects with iron deficiency anemia in infancy. Frontiers in aging neuroscience. 2017 Mar 7;9:54.
Karshalev E, Zhang Y, Esteban-Fernández de Ávila B, Beltrán-Gastélum M, Chen Y, Mundaca-Uribe R, Zhang F, Nguyen B, Tong Y, Fang RH, Zhang L. Micromotors for active delivery of minerals toward the treatment of iron deficiency anemia. Nano letters. 2019 Oct 7;19(11):7816-26.
Shafi M, Taufiq F, Mehmood H, Afsar S, Badar A. Relation between depressive disorder and iron deficiency anemia among adults reporting to a secondary healthcare facility: a hospital-based case-control study. J Coll Physicians Surg Pak. 2018 Jun 1;28(6):456-559.
Tariq S, Isran BZ, Kiani SN, Shabir R. Maternal Anemia and Risk of Small for Gestational Age. Annals of King Edward Medical University. 2022 Aug 4;28(2):200-4.
Sattar S, Sultana S, Shadab W, Afzal S, Salma UE, Mobeen A. Comparison of Safety and Efficacy of Ferric Carboxymaltose with Iron Sucrose for the Treatment of Iron Deficiency Anemia in Pregnancy. InMed. Forum 2023 Feb 16 (Vol. 34, No. 2).
Mahmood T, Rehman AU, Tserenpil G, Siddiqui F, Ahmed M, Siraj F, Kumar B. The association between iron-deficiency anemia and adverse pregnancy outcomes: a retrospective report from Pakistan. Cureus. 2019 Oct 7;11(10).
Rukuni R, Bhattacharya S, Murphy MF, Roberts D, Stanworth SJ, Knight M. Maternal and neonatal outcomes of antenatal anemia in a Scottish population: a retrospective cohort study. Acta obstetricia et gynecologica Scandinavica. 2016 May;95(5):555-64.
Räisänen S, Kancherla V, Gissler M, Kramer MR, Heinonen S. Adverse Perinatal Outcomes Associated with Moderate or Severe Maternal Anaemia Based on Parity in F inland during 2006–10. Paediatric and perinatal epidemiology. 2014 Sep;28(5):372-80.
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