Abstract
Objective:
To evaluate the effect of tonsillectomy on anti-streptolysin O (ASO) titre levels in children.
Methodology:
48 patients 5 -15 years of age with ASO titre > 200IU/ml undergoing elective tonsillectomy were included in the study.ASO titre was measured at 1 month, 2 months and 3 months after tonsillectomy. Data analysis was done at SPSS 21. P-value of < 0.05 was taken as significant.
Results:
After tonsillectomy reduction of ASO titre to less than 200IU/ml occurred in 3 (6%), 27 (56%) and 46 (96%) patients at 1st, 2nd and 3rd monthly follow up respectively.
Conclusion:
Tonsillectomy significantly reduces ASO titre levels in pediatric patients with recurrent tonsillitis. This reduction suggests that tonsillectomy can effectively mitigate the immune response to streptococcal infections.

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