Official publication of Rawalpindi Medical University
Analgesic Efficacy Of Preoperative Versus Postoperative Ultrasound-Guided Transverse Abdominis Plane Block For Laparoscopic Cholecystectomy

How to Cite

1.
Palijo MK, Feroze F, Faheem MSB, Faheem S, Khalid M, Farooq S. Analgesic Efficacy Of Preoperative Versus Postoperative Ultrasound-Guided Transverse Abdominis Plane Block For Laparoscopic Cholecystectomy. JRMC [Internet]. 2025 Dec. 31 [cited 2025 Dec. 31];29(4). Available from: https://journalrmc.com/index.php/JRMC/article/view/2880

Abstract

Objective: In enhanced recovery procedures, the transversus abdominis plane (TAP) block is applied as one of the multimodal pain control techniques. The study evaluated whether administering an ultrasound-guided TAP block before or after laparoscopic cholecystectomy is more effective for managing postoperative pain within enhanced recovery protocols.

Methods: A prospective study was conducted at PAF Hospital Mushaf Sargodha between July 2024 and December 2024. Patients who met the criteria for laparoscopic cholecystectomy were split randomly into two groups (n=50 for each group). Patients in the preoperative group (PG) had a bilateral ultrasound-guided transversus abdominis plane block performed with 20 cc of bupivacaine 0.25% performed on them after the induction of general anaesthesia. A visual analogue scale was used to evaluate the patients’ levels of pain when they were first brought into the recovery room, as well as after four, eight, twelve, and twenty-four hours had passed. The pain score recorded in the recovery room as well as at the 4th, 8th, 12th, and 24th hours is the primary outcome.

Result: The ultrasound-guided TAP block resulted in a significantly reduced pain score in the POG group in comparison to the PG group with stable hemodynamic parameters (heart rate and mean arterial pressure). Following the operation, the POG patients reported significantly less pain when coughing at 4,8,12 and 24 hours. The POG consistently had considerably higher levels of patient satisfaction across the board. Patients in the POG had much lower rates of post-operative nausea and vomiting and required a longer time duration before rescuing analgesic demand than patients in the PG group.

Conclusion: When it comes to giving postoperative analgesia, our study suggested that postoperative TAP block is more effective than preoperative TAP block.

Keywords: analgesic, ultrasound, Laparoscopic cholecystectomy

https://doi.org/10.37939/jrmc.v29i4.2880

References

Shao P, Jiang J, Shi R, Hu J, Li H, Guo R, et al. Postoperative analgesic effects of combined transversus abdominis plane block and anterior approach of sacral plexus block in patients undergoing laparoscopic radical prostatectomy: A randomized controlled trial. J Clin Anesth. 2025 Jun;104:111864. Doi: 10.1016/j.jclinane.2025.111864. Epub 2025 May 9. PMID: 40347560.

Pickett C, Patanwala I, Kasper K, Haas DM. Transversus abdominis plane (TA P) blocks for prevention of postoperative pain in women undergoing laparoscopic and robotic gynaecological surgery. Cochrane Database Syst Rev. 2022 Nov 21;2022(11): CD015145. Doi: 10.1002/14651858.CD015145. PMCID: PMC9677949.

Chin KJ, McDonnell JG, Carvalho B, Sharkey A, Pawa A, Gadsden J. Essentials of Our Current Understanding: Abdominal Wall Blocks. Reg Anesth Pain Med. 2017 Mar/Apr;42(2):133-183. Doi: 10.1097/AAP.0000000000000545. PMID: 28085788.

Shrestha BB, Lakhe G, Ghimire P. Postoperative Pain after Laparoscopic Cholecystectomy in a Tertiary Care Center: A Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc. 2024 Jul 31;62(276):502-506. Doi: 10.31729/jnma.8719. PMID: 39369396; PMCID: PMC11455656.

Mavarez AC, Hendrix JM, Ahmed AA. Transabdominal Plane Block. 2023 Nov 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 32809362.

Emile SH, Elfeki H, Elbahrawy K, Sakr A, Shalaby M. Ultrasound-guided versus laparoscopic-guided subcostal transversus abdominis plane (TAP) block versus No TAP block in laparoscopic cholecystectomy; a randomized double-blind controlled trial. Int J Surg. 2022 May;101:106639. Doi: 10.1016/j.ijsu.2022.106639. Epub 2022 Apr 27. PMID: 35487422.

Vindal A, Sarda H, Lal P. Laparoscopically guided transversus abdominis plane block offers better pain relief after laparoscopic cholecystectomy: results of a triple blind randomized controlled trial. Surg Endosc. 2021 Apr;35(4):1713-1721. Doi: 10.1007/s00464-020-07558-9. Epub 2020 Apr 15. PMID: 32297054.

Suseela I, Anandan K, Aravind A, Kaniyil S. Comparison of ultrasound-guided bilateral subcostal transversus abdominis plane block and port-site infiltration with bupivacaine in laparoscopic cholecystectomy. Indian J Anaesth. 2018 Jul;62(7):497-501. Doi: 10.4103/ija.IJA_55_18. PMID: 30078851; PMCID: PMC6053890.

Bourgeois C, Oyaert L, Van de Velde M, Pogatzki-Zahn E, Freys SM, Sauter AR, et al. Pain management after laparoscopic cholecystectomy: A systematic review and procedure-specific postoperative pain management (PROSPECT) recommendations. Eur J Anaesthesiol. 2024;41(11):841-855. Doi: 10.1097/EJA.0000000000002047. PMID: 39129451.

Xu H, Song D, Wu Z, Lin C, Fu W, Wang F. Comparison of postoperative analgesic effects of ultrasound-guided intercostal nerve block and transversus abdominis plane block in patients undergoing laparoscopic cholecystectomy: randomized clinical trial. BJS Open. 2025 Jul 1;9(4):zraf022. Doi: 10.1093/bjsopen/zraf022. PMID: 40591374; PMCID: PMC12211735.

Pirrera B, Alagna V, Lucchi A, Berti P, Gabbianelli C, Martorelli G, et al. Transversus abdominis plane (TAP) block versus thoracic epidural analgesia (TEA) in laparoscopic colon surgery in the ERAS program. Surg Endosc. 2018;32(1):376-382. doi: 10.1007/s00464-017-5686-7. PMID: 28667547.

Kalu R, Boateng P, Carrier L, Garzon J, Tang A, Reickert C, et al. Effect of preoperative versus postoperative use of transversus abdominis plane block with plain 0.25 % bupivacaine on postoperative opioid use: a retrospective study. BMC Anesthesiol. 2021 Apr 12;21(1):114. Doi: 10.1186/s12871-021-01333-6. PMID: 33845790. PMCID: PMC8040194.

Rahimzadeh P, Faiz SHR, Latifi-Naibin K, Alimian M. A Comparison of effect of preemptive versus postoperative use of ultrasound-guided bilateral transversus abdominis plane (TAP) block on pain relief after laparoscopic cholecystectomy. Sci Rep. 2022 Jan 12;12(1):623. Doi: 10.1038/s41598-021-04552-6. PMID: 35022459; PMCID: PMC8755749.

Ambooken E, Chirayath JJ, Raghavan P. A comparison of preincisional and postincisional ultrasound guided transversus abdominis plane block. J Anaesthesiol Clin Pharmacol. 2021 Jul-Sep;37(3):406-410. Doi: 10.4103/joacp.JOACP_283_19. Epub 2021 Oct 12. PMID: 34759552; PMCID: PMC8562456.

Priyanka BG, Krishnamurthy PKD, Rohit S. Comparative Study of Pre-Operative Ultrasound Guided Transversus Abdominis Plane Block Versus Post-Operative Ultrasound Guided Transversus Abdominis Plane Block on Perioperative Hemodynamic Status and Post Operative Analgesic Requirement in Patients Undergoing Laparoscopic Abdominal Surgeries. Eur J Mol Clin Med. 2022;9:2781-2789. Available online: https://ejmcm.com/article_17726.html (accessed on 17 August 2022).

John R, Ranjan RV, Ramachandran TR, George SK. Analgesic Efficacy of Transverse Abdominal Plane Block after Elective Cesarean Delivery – Bupivacaine with Fentanyl versus Bupivacaine Alone: A Randomized, Double-blind Controlled Clinical Trial. Anesth Essays Res. 2017 Jan-Mar;11(1):181-184. Doi: 10.4103/0259-1162.186864. PMID: 28298781; PMCID: PMC5341662.

Wang P, Chen X, Chang Y, Wang Y, Cui H. Analgesic efficacy of ultrasound-guided transversus abdominis plane block after cesarean delivery: A systematic review and meta-analysis. J Obstet Gynaecol Res. 2021 Sep;47(9):2954-2968. Doi: 10.1111/jog.14881. Epub 2021 Jun 15. PMID: 34128297.

El Sharkwy IA, Noureldin EH, Mohamed EA, et al. Laparoscopic-guided transversus abdominis plane block versus trocar site local anesthetic infiltration in gynecologic laparoscopy. Gynecol Surg. 2018;15:15. doi: 10.1186/s10397-018-1047-3.

Cai Q, Gao ML, Chen GY, Pan LH. Transversus Abdominis Plane Block versus Wound Infiltration with Conventional Local Anesthetics in Adult Patients Underwent Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Biomed Res Int. 2020 Mar 23;2020:8914953. Doi: 10.1155/2020/8914953. PMID: 32280705; PMCID: PMC7125448.

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Copyright (c) 2025 Muhammad Khalid Palijo, Faheem Feroze, Muhammad Shaheed Bin Faheem, Saadia Faheem, Maliha Khalid, Saeed Farooq