Abstract
Objective: To determine the diagnostic accuracy of the internal jugular vein collapsibility index for the diagnosis of hypovolaemia in intensive care unit patients using central venous pressure as the gold standard.
Method: This cross-sectional validation study was conducted at the Department of Anesthesiology, Benazir Bhutto Hospital. IJV-CI was calculated as the percentage reduction in vein diameter from expiration to inspiration in the supine, 30° head-up position. Hypovolemia was defined as a CVP of < 8 mmHg.
Results: Of the 150 participants, 46.7% (n=70) were hypovolemic according to the CVP criteria. IJV-CI had a sensitivity of 52.9%, specificity of 85.0%, positive predictive value (PPV) of 75.5%, negative predictive value (NPV) of 67.3%, and accuracy of 70.0%. The mean IJV-CI was higher in hypovolemic patients than in non-hypovolemic patients (40.8% vs. 29.1%; p < 0.001). The Area Under the Curve (AUC) was 0.783.
Conclusion: IJV-CI is a useful noninvasive tool for detecting hypovolaemia in ICU patients, demonstrating good overall discriminative power.
Keywords: Hypovolemia; Central Venous Pressure; Jugular Veins; Ultrasonography; Intensive Care Units; Sensitivity and Specificity; Hemodynamics
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Copyright (c) 2026 Mahnoor Zahid, Abeera Zareen, Tehreem Zahid, Kainat Altaf, Hamna Sarwar, Saba Shafiq

