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Postpartum Secondary PPH Leading to Diagnosis of Choriocarcinoma: A Case Report

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1.
Maqsood Z, Farkhanda T, Ejaz S, Kousar T, Malik SN, Bilqis H. Postpartum Secondary PPH Leading to Diagnosis of Choriocarcinoma: A Case Report. JRMC [Internet]. 2026 Feb. 14 [cited 2026 Feb. 24];1(1). Available from: https://journalrmc.com/index.php/JRMC/article/view/3190

Abstract

Summary: One uncommon but extremely aggressive kind of gestational trophoblastic neoplasia (GTN) is postpartum choriocarcinoma. Its clinical manifestation frequently resembles typical subsequent postpartum hemorrhage sources, which could impede identification and raise maternal morbidity.

Case Presentation:

A woman with a history of three prior cesarean sections appeared with recurring severe vaginal bleeding. Twelve days after an emergency cesarean delivery, Conservative management was started after an initial examination revealed retained products of conception. However, hypovolemic shock caused the patient's condition to worsen. Suspicion of GTN was raised by significantly high levels of β-human chorionic gonadotropin (β- hCG) in the serum and pelvic magnetic resonance imaging. An urgent surgical procedure was carried out since the bleeding was potentially fatal.

Keywords: Postpartum Hemorrhage, beta-Human Chorionic Gonadotropin, Cesarean Section, Choriocarcinoma, Gestational Trophoblastic Neoplasia

https://doi.org/10.37939/jrmc.v1i1.3190

References

Seckl MJ, Sebire NJ, Fisher RA. Gestational trophoblastic disease: current management and future directions. Lancet Oncol. 2021;22(6):e284-e293. https://doi.org/10.1016/S1470- 2045(20)30656-8

FIGO Oncology Committee. FIGO staging for gestational trophoblastic neoplasia 2018: update and clinical implications. Int J Gynaecol Obstet. 2021;155(Suppl 1):86-93. https://doi.org/10.1002/ijgo.13883

Ngan HYS, Seckl MJ, Berkowitz RS, et al. Update on the diagnosis and management of gestational trophoblastic disease. Int J Gynaecol Obstet. 2021;155(Suppl 1):S1-S11. https://doi.org/10.1002/ijgo.13877

Froeling FEM, Ramasamy R, Kaur B, et al. Imaging of gestational trophoblastic disease: current role and future perspectives. Radiographics. 2022;42(2):452-470. https://doi.org/10.1148/rg.210108

Mangili G, Lorusso D, Brown J, et al. Postpartum choriocarcinoma: clinical features, diagnosis, and management. Gynecol Oncol. 2021;161(2):453-458. https://doi.org/10.1016/j.ygyno.2021.02.015

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Copyright (c) 2026 Zainab Maqsood, Tallat Farkhanda, Sara Ejaz, Tayyaba Kousar, Sobia Nawaz Malik, Humaira Bilqis