Official publication of Rawalpindi Medical University
Polypharmacy And Its Impact On Medication Non-Adherence: A Cross-Sectional Study

How to Cite

1.
Mughal FAR, Rehman A. Polypharmacy And Its Impact On Medication Non-Adherence: A Cross-Sectional Study. JRMC [Internet]. 2026 Jun. 30 [cited 2026 Jun. 30];30(2). Available from: https://journalrmc.com/index.php/JRMC/article/view/3116

Abstract

Objective: To determine the association between polypharmacy and medication non-adherence in pregnant women in Rawalpindi, Pakistan.

Methods: A cross-sectional study was conducted by the Department of Community Medicine, Foundation University Medical College, Rawalpindi, over six months. Using non-probability sampling, one hundred and forty pregnant women in their second or third trimester of pregnancy were included in the study. A pre-validated questionnaire, which included informed consent, was used for the data collection. Using SPSS version 26.0, descriptive statistics, chi-square test of association, and logistic regression were performed, with a p-value of <0.05 considered significant.

Results: The mean age of the participants was 30 years (SD + 5.190. Around 22.56% of the respondents reported polypharmacy (> 3 medicines). Of the respondents taking three or more drugs, 60.6% reported non-adherence. The chi-square test of independence showed a significant association between polypharmacy and medication non-adherence (P < 0.001).

Conclusion: Polypharmacy plays an important role in medication non-adherence, as established in our study.

Keywords: Iron Folic Acid, Medication Adherence, Pregnancy, Polypharmacy

https://doi.org/10.37939/jrmc.v30i2.3116

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Copyright (c) 2026 Fatima Ali Raza Mughal, Anila Rehman